tricarboxylic acid cycle

1. At present, we consider NO released by activated macrophages can kill target cells by restraining the tricarboxylic acid cycle, electron transfer and composition of DNA in target cells.
   目前认为，经激活的巨噬细胞释放的NO可以通过抑制靶细胞线粒体中三羧酸循环、电子传递和细胞DNA合成等途径，发挥杀伤靶细胞的效应。
2. MtDNA mutation result in insulin deficiency by tricarboxylic acid cycle ( TCA cycle) obstruction.
   线粒体基因突变可通过三羧酸循环障碍导致β细胞分泌胰岛素不足。
3. Tricarboxylic acid ( TCA) cycle is an important way to generate ATP, which is widely distributed in the cells of animal, plant or microorganism.
   在动物、植物、微生物细胞中普遍存在的三羧酸循环（TCA循环）是产生ATP的主要途径，它不仅参与糖的分解代谢，也参与蛋白质和脂肪的分解代谢。
4. Moreover, Amino acid, as a tricarboxylic acid cycle substate, has been proved to be able reduce impairment of reperfusion in infant myocardium protection.
   另外氨基酸作为心肌有氧代谢的三羧酸循环底物，在婴幼儿心肌保护中因能明显减轻缺血、缺氧心肌的再灌注损伤而日益受到重视。
5. Acetyl CoA into the tricarboxylic acid cycle provides energy for metabolism of organisms.
   然后乙酰辅酶A再进入三羧酸循环为生物体新陈代谢提供能源。
6. All above described changes of the metabolic components indicated that restraint stress led to glycolysis 、 gluconeogenesis capacity 、 tricarboxylic acid cycle as well as the disorder of lipid metabolism disordered.
   这些代谢成分的改变提示束缚应激可导致能量代谢中糖酵解、糖异生能力、三羧酸循环的改变以及肝脏脂代谢的紊乱。
7. In addition, about half of the enzymes and coenzymes in the tricarboxylic acid cycle contain iron or need the presence of iron.
   此外，参加三羧酸循环的酶和辅酶约半数含有铁或需要铁的存在。
8. Malate dehydrogenase ( MDH) is the key enzyme of tricarboxylic acid cycle ( TCA), which is commonly observed in living organisms.
   苹果酸脱氢酶（MDH）是三羧酸循环中的一个关键酶，在生物体内普遍存在，MDH以NADH或NAD+为辅因子，催化苹果酸盐与草酰乙酸盐的相互转化。
9. The increased recent studies in vitro have showed that Al ( III) could inhibit the activity of enzyme which catalyzed the tricarboxylic acid cycle ( TCA) and glycolytic cycle, thereby the production of energy generated by mitochondrial cell was badly affected.
   越来越多的体外研究表明，铝能够抑制三羧酸循环和糖酵解过程中酶的活性，因此线粒体细胞供能系统受到严重的阻碍。

noun

1. in all plants and animals: a series of enzymatic reactions in mitochondria involving oxidative metabolism of acetyl compounds to produce high-energy phosphate compounds that are the source of cellular energy

   Synonym:    Krebs cycleKrebs citric acid cyclecitric acid cycle